National Antimicrobial Treatment Guidelines 2023

National  Antimicrobial  Treatment Guidelines  2023

Contents

List of Abbreviations

i

Introduction

v

General Principles vi

Administration of Antibiotics vii

Antimicrobial Stewardship viii

Approach to Multidrug Resistant Organisms ix

Infections in Adults

Respiratory Tract Infections

1

Cardiovascular System Infections

5

Central Nervous Infections 10

Oral/Dental Infections 14

Ocular Infections 18

Otorhinolaryngological Infections 25

Gastrointestinal Tract Infections 30

Surgical Infections in Adult 34

Urinary Tract Infections 46

Infections in Immunocompromised Patients 49

Chemoprophylaxis : Surgical 53

Chemoprophylaxis : Non Surgical 65

Obstetric and Gynaecological Infections 67

Skin and Soft Tissue Infections 75

Tropical and Other Infections 89

HIV Infection in Adults 95

Infections in Peadiatric Age Group

Respiratory Tract Infection 109

Cardiovascular System Infections 112

Central Nervous System Infections 116

Ocular Infections 119

Otorhinolaryngological Infections 120

Gastrointestinal Tract Infections 122

Surgical Infections in Children 126

Urinary Tract Infections 128

Neonatal Infections 129

Chemoprophylaxis: Surgical 135

Chemoprophylaxis: Non-Surgical 139

Skin and Soft Tissue Infections 146

Tropical and Other Infections 149

Infections in Immunocompromised Patients 164

Appendix

AWaRe Classification – WHO 166

Antibiotics Not Recommended (WHO List-2021) 171

Adverse Drug Reactions Reporting Form 174

Useful Links of National and International Guidelines 176

Therapeutic Guideline Development Committee 177

Acknowledgement 178

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NATIONAL ACTION PLAN FOR ANTIMICROBIAL RESISTANCE NEPAL 2021-2026